Falk Butter

This study shows HOT1 functions as a homodimer to maintain an ALT-permissive chromatin state at telomeres.

The paper shows that GTSF-1 binds RRF-3 in nematodes, a conserved interaction essential for 26G-RNA production and fertility.

This study identifies ZNF512B as a spindle-associated protein that regulates metaphase exit and stem cell differentiation, independent of its zinc finger domains and NuRD complex interaction.

The paper identifies RNA-binding proteins interacting with pri-miRNAs in Arabidopsis and develops an improved iCLIP protocol to map their binding sites.

This study identifies SET-24, a catalytically inactive SET domain protein in C. elegans, as essential for maintaining transgenerational epigenetic memory through its interaction with HCF-1 and regulation of H3K4me3 levels.

The paper investigates the developmental dynamics and crosstalk between WAGO-1 and WAGO-3 in C. elegans, showing distinct regulatory roles and complex interactions with 22G-RNAs and 26G-RNAs.

This study identifies Gid11 as a substrate receptor for the GID ubiquitin ligase in budding yeast, revealing its role in regulating metabolic transitions by targeting glycolytic factors during ethanol metabolism.

The paper identifies ERH and associated factors as post-transcriptional regulators of JAK2 mRNA maturation, essential for IFNγ signaling and innate immunity.

This paper identifies TAC53 as a novel component of the Tripartite Attachment Complex (TAC) in Trypanosoma brucei, revealing its tubular architecture and role in mitochondrial DNA segregation.

The paper identifies recurrent capture of transposable element domains by F-box genes across eukaryotes and shows their functional integration into host regulatory networks.

The paper investigates the dynamic co-evolution of transposable elements and the piRNA pathway in African cichlid fishes, revealing expanded piwil1 genes and divergent piRNA-producing loci.

This study shows that DOT1B is not essential for differentiation or macrophage infection in Leishmania mexicana, contrasting its essential role in Trypanosoma brucei.

The paper identifies ICOP1 and ICOP2 as proteins interacting with ISWI1 that are essential for chromatin remodeling and DNA elimination during somatic genome development in Paramecium.

The paper identifies TelAP2 as an interacting partner of TelAP1 in the telomere complex of Trypanosoma brucei and shows that TelAP1 requires this interaction to associate with telomeric proteins.

This study identifies ZNF512B as a repressor of gene expression that interacts with the NuRD complex via a conserved motif and can cause chromatin aggregation independently of NuRD.

The paper identifies proteins interacting with the AtGRP7 mRNA in Arabidopsis using enhanced RNA interactome capture, revealing ALBA proteins as binders.

The paper identifies Msc1 as a nuclear envelope protein that enhances DNA repair in late mitosis by supporting homologous recombination.

The paper identifies PUCH, a trimeric Schlafen-domain nuclease that initiates piRNA processing in C. elegans by cleaving 5-end piRNA precursors, revealing a novel RNA endonuclease mechanism.

The paper identifies LOTR-1, a C. elegans protein with LOTUS and Tudor domains, which interacts with ZNFX-1 to regulate small RNA processing in the germline.

The paper examines transcriptional activity and epigenetic regulation of transposable elements in the symbiotic fungus Rhizophagus irregularis, finding evidence of TE activity and epigenomic regulation.

This study identifies chromatin modifiers and recombination factors essential for telomere folding in yeast, which is lost during replicative senescence.

This study identifies MAZ as a novel transcription factor regulating erythropoiesis by binding to the -globin gene promoter and interacting with GATA1-bound enhancers, with knockdown impairing differentiation and genetic variants linked to erythroid traits.

This study identifies RPB-9 as essential for piRNA-mediated silencing in C. elegans by promoting transcriptional elongation/termination at piRNA loci.

The paper identifies PID-2 and related proteins as essential for establishing and maintaining RNAe in C. elegans embryos through interactions with eTudor domain proteins and proteolysis.

This study shows that the m6A reader Ythdf limits axonal growth in Drosophila by modulating Fmr1 target selection.

The paper identifies PETISCO as a novel protein complex essential for 21U RNA biogenesis and embryonic viability in C. elegans, revealing its distinct roles from PID-1.

This study identifies Tdrd6a as a regulator of Buc protein aggregation, which is essential for forming subcellular compartments that drive germ cell specification in zebrafish.

The paper identifies genome-wide phased nucleosome arrays in Drosophila, revealing a novel sequence motif and the role of the zinc finger protein Phaser in their formation.