Nrf2 promotes thyroid development and hormone synthesis.
Pierre Gillotay, Mírian Romitti, Dassy Benjamin, Benoît Haerlingen, Meghna Shankar, Bárbara F. Fonseca, Panos G. Ziros, Sumeet Pal Singh, Gerasimos P. Sykiotis, Sabine Costagliola
This study shows that NRF2 regulates thyroglobulin expression in zebrafish and mouse thyroid organoids to manage oxidative stress during thyroid hormone synthesis.
bioRxiv · Feb 27, 2022 · PreprintDevelopmental Biology