David A. Magee

High-resolution transcriptomics of bovine purified protein derivative-stimulated peripheral blood from cattle infected with Mycobacterium bovis across an experimental time course

The paper identifies a 170-gene transcriptional signature in bovine peripheral blood post-M. bovis infection following PPD-b stimulation, suggesting potential biomarkers for bTB diagnostics.

A Population Genomics Analysis of the Native Irish Galway Sheep Breed

This study uses population genomics to analyze the Galway sheep breed, finding gene flow from British Leicester and Suffolk sheep, intermediate genetic diversity, and genomic signatures of selection related to meat and wool production.

The bovine alveolar macrophage DNA methylome is resilient to infection with Mycobacterium bovis

This study examines the DNA methylome of bovine alveolar macrophages infected with Mycobacterium bovis and finds no significant changes in DNA methylation, but identifies genes with intermediate promoter methylation enriched for immune-related functions.

RNA sequencing (RNA-seq) reveals extremely low levels of reticulocyte-derived globin gene transcripts in peripheral blood from horses (Equus caballus) and cattle (Bos taurus)

The paper assesses globin mRNA impact on RNA-seq in horses and cattle, finding low levels that eliminate the need for globin depletion.

Comparative omics analyses differentiate Mycobacterium tuberculosis and Mycobacterium bovis and reveal distinct macrophage responses to infection with the human and bovine tubercle bacilli

This study compares the transcriptomic and proteomic profiles of Mycobacterium tuberculosis and Mycobacterium bovis, revealing distinct host responses in bovine macrophages.

Genomic characterisation and conservation genetics of the indigenous Irish Kerry cattle breed

This study uses genome-wide SNP data to assess genetic diversity and conservation status of Kerry cattle, revealing reduced effective population size and increased inbreeding.