Author

Eamonn P. Gormley

University College DublinORCID 0000-0003-3900-0393Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 4 Research Focus:differential expression· 3 Approach:statistical model· 3 Research Focus:benchmarking· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1 Approach:machine learning (classical)· 1 Assay:proteomics· 1

Frequent Co-Authors

David Evan MacHughiD· 4 shared Stephen Vincent GordoniD· 4 shared Carolina N. CorreiaiD· 3 shared Gillian P. McHugoiD· 3 shared John Arthur BrowneiD· 3 shared David A. Magee· 2 shared Emily L. ClarkiD· 2 shared Hubert PauschiD· 2 shared

Activity by Year

2018-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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4 shared papersGenomics

David Evan MacHughORCID

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4 papers

Recent·Most cited

GenomicsbioRxivPreprintSep 1, 2025

A new diagnostic modality for bovine tuberculosis: accurate and robust classification of infected cattle using transcriptomics and machine learning

John Francis O'Grady, Adriana Ivich, Gillian P. McHugo…·David Evan MacHugh

The paper develops mRNA-based classifiers using RNA-seq and machine learning to accurately distinguish bTB-positive from bTB-negative cattle and other pathogens.

DOI 10.1101/2025.09.01.673540

bulk RNA-seqmachine learning (classical)

𝕏 PostBluesky

GenomicsCommunications BiologyPeer-reviewedMar 24, 2025

Integrative genomics sheds light on the immunobiology of tuberculosis in cattle

John Francis O'Grady, Gillian P. McHugo, James A. Ward…·David Evan MacHugh

This study integrates transcriptomic, genomic, and GWAS data to identify genes and eQTLs associated with the PB transcriptome response to M. bovis infection in cattle.

10 citationstop 2%

bulk RNA-seqstatistical model

𝕏 PostBluesky

GenomicsTuberculosisPeer-reviewedJul 30, 2022

High-resolution transcriptomics of bovine purified protein derivative-stimulated peripheral blood from cattle infected with Mycobacterium bovis across an experimental time course

Carolina N. Correia, Gillian P. McHugo, John Arthur Browne…·David Evan MacHugh

The paper identifies a 170-gene transcriptional signature in bovine peripheral blood post-M. bovis infection following PPD-b stimulation, suggesting potential biomarkers for bTB diagnostics.

11 citations

bulk RNA-seqstatistical model

𝕏 PostBluesky

Systems BiologyMicrobial GenomicsPeer-reviewedMar 1, 2018

Comparative omics analyses differentiate Mycobacterium tuberculosis and Mycobacterium bovis and reveal distinct macrophage responses to infection with the human and bovine tubercle bacilli

Kerri M. Malone, Kévin Rue-Albrecht, David A. Magee…·Stephen Vincent Gordon

This study compares the transcriptomic and proteomic profiles of Mycobacterium tuberculosis and Mycobacterium bovis, revealing distinct host responses in bovine macrophages.

68 citationstop 3%

bulk RNA-seqproteomics

𝕏 PostBluesky