PRMT1 Modulates Alternative Splicing to Enhance HPV18 mRNA Stability and Promote the Establishment of Infection
David E.J. Williams, Kelly M. King, Robert Jackson, Franziska Kuehner, Christina R. Arnoldy, Jaclyn N. Marroquin, Isabelle G. Tobey, Amy Banka, Sofia Ragonese, Koenraad Van Doorslaer
This study identifies PRMT1 as a critical factor in HPV18 infection by modulating alternative splicing and mRNA stability, promoting persistent infection in primary human cervical cells.
bioRxiv · Sep 26, 2024 · PreprintMicrobiology