Author

David Grynspan

Children's Hospital of Eastern Ontario

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Akasham Rajagopaul· 1 shared Andrew Rutman· 1 shared Barbra de VrijeriD· 1 shared Christopher Mark WatsoniD· 1 shared Christopher O’CallaghaniD· 1 shared Chunmei LiiD· 1 shared David T. BonthroniD· 1 shared Eamonn G. SheridaniD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperPhysiology

Akasham Rajagopaul

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2 papers

Recent·Most cited

Altered placental morphology and metabolomic profile in as-sociation with uncomplicated metabolically healthy obese pregnancy

Ousseynou Sarr, Akasham Rajagopaul, Shuang Zhao, Xiaohang Wang, David Grynspan, Genevieve D. M. Eastabrook, Li Liang, Timothy R.H. Regnault, Barbra de Vrijer

This study identifies altered placental morphology and metabolomic profiles in metabolically healthy obese pregnancies, highlighting unique metabolic pathways and potential biomarkers.

bioRxiv · Mar 20, 2025 · PreprintPhysiology

Biallelic Mutations in LRRC56 encoding a protein associated with intraflagellar transport, cause mucociliary clearance and laterality defects

Serge Bonnefoy, Christopher Mark Watson, Kristin D. Kernohan, Moara Lemos, Sebastian Hutchinson, James A. Poulter, Laura A. Crinnion, Ian R Berry, Jennifer Simmonds, Pradeep C. Vasudevan, Christopher O’Callaghan, Robert Anthony Hirst, Andrew Rutman, Lijia Huang, Taila Hartley, , Eamonn G. Sheridan

The paper identifies biallelic LRRC56 mutations causing ciliary dysfunction and laterality defects in two families, linking LRRC56 to intraflagellar transport and dynein arm assembly.

The American Journal of Human Genetics · Nov 1, 2018Peer-reviewedGenetics