Author
UCSF Benioff Children's Hospital
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
Stacia K. Wyman, Zulema G. Romero, Seok‐Jin Heo…·Dario Boffelli
This study identifies synthesis errors in ssODNs used for HDR-mediated gene editing and shows they propagate into the genome, potentially causing disease alleles.
Joseph T.C. Shieh, Monica Penon‐Portmann, Karen H. Y. Wong…·Dario Boffelli
This study evaluates the Full Genome Analysis method for diagnosing rare monogenic disorders, finding a 40% diagnostic yield in clinical cases.
Jennifer E. Chung, Wendy Magis, Jonathan T. Vu…·Mark A. DeWitt
This study uses CRISPR-Cas9 to test a putative fetal globin repressor region, finding it does not autonomously silence gamma-globin, suggesting it is not a therapeutic target for beta-hemoglobinopathies.
Wendy Magis, Mark A. DeWitt, Stacia K. Wyman…·David I. K. Martin
Cas9-mediated correction of the sickle mutation in human hematopoietic stem cells achieves curative levels of editing.