Author

David J. Krause

University of Wisconsin–Madison

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Research Focus:variant calling· 2 Organism:bacteria (other)· 1 Assay:CRISPR screen· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:multiple species· 1

Frequent Co-Authors

Audrey P. GaschiD· 1 shared Changyi ZhangiD· 1 shared Chris Todd HittingeriD· 1 shared Gianni LitiiD· 1 shared Hayley R StonemaniD· 1 shared Joseph SchachereriD· 1 shared Matteo De ChiaraiD· 1 shared Michael Graham· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenetics

Audrey P. GaschORCID

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2 papers

Recent·Most cited

Analyses of Genome-Wide Recombination in Sulfolobus islandicus

David J. Krause, Changyi Zhang, Rachel J. Whitaker

The paper analyzes recombination patterns in Sulfolobus islandicus by sequencing recombinant strains and using a new tool to identify breakpoints, revealing uniform recombination rates and short tract preferences.

bioRxiv · Dec 16, 2025 · PreprintMicrobiology

CRISpy-pop: a web tool for designing CRISPR/Cas9-driven genetic modifications in diverse populations

Hayley R Stoneman, Russell L. Wrobel, Michael Place, Michael Graham, David J. Krause, Matteo De Chiara, Gianni Liti, Joseph Schacherer, Robert C. Landick, Audrey P. Gasch, Trey K. Sato, Chris Todd Hittinger

CRISpy-pop designs and predicts CRISPR/Cas9 guide RNA activity across diverse yeast and bacterial strains, including human genome cross-referencing for biosafety.

G3 Genes Genomes Genetics · Sep 22, 2020Peer-reviewedGenetics