Russell L. Wrobel

This study uses machine learning to identify gene families associated with oxidative stress resistance in yeasts and validates their roles experimentally.

CRISpy-pop designs and predicts CRISPR/Cas9 guide RNA activity across diverse yeast and bacterial strains, including human genome cross-referencing for biosafety.

The paper constructs six-species synthetic yeast hybrids and shows they are chromosomally unstable but can rapidly adapt to novel environments.