Author

David R. Martinez

Duke UniversityPrimary ORCID profile (0000-0002-2940-8961 · 5 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

David R. MartineziD5 papers · Yale University

Biology Disciplines

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Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:proteomics· 1

Frequent Co-Authors

Sallie R. PermariD· 2 shared Amit KumariD· 1 shared Ayooluwa O. DouglasiD· 1 shared Celia C. LaBrancheiD· 1 shared Claire E.P. SmithiD· 1 shared David C. MontefioriiD· 1 shared Elena E. GiorgiiD· 1 shared Erin A. Harrell· 1 shared

Activity by Year

2018-2018 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMicrobiology

Sallie R. PermarORCID

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2 papers

Recent·Most cited

IgG is differentially and selectively transferred across the placenta in HIV-infected women

David R. Martinez, Youyi Fong, Shuk Hang Li, Fang Yang, Madeleine Jennewein, Joshua A. Weiner, Erin A. Harrell, Jesse F. Mangold, Ria Goswami, George Seage, Galit Alter, Margaret E. Ackerman, Xinxia Peng, Genevieve G. Fouda, Sallie R. Permar

This study identifies factors affecting placental IgG transfer efficiency in HIV-infected women, showing that maternal disease progression and Fc region characteristics influence selective transfer of antigen-specific IgG.

bioRxiv · Nov 30, 2018 · PreprintMicrobiology

Infant Transmitted/Founder HIV-1 Viruses from Peripartum Transmission are Neutralization Resistant to Paired Maternal Plasma

Amit Kumar, Claire E.P. Smith, Elena E. Giorgi, Joshua Eudailey, David R. Martinez, Karina Yusim, Ayooluwa O. Douglas, Lisa Stamper, Erin McGuire, Celia C. LaBranche, David C. Montefiori, Genevieve G. Fouda, Feng Gao, Sallie R. Permar

The paper identifies infant-transmitted HIV-1 variants that are neutralization-resistant to maternal plasma but sensitive to broadly neutralizing antibodies, suggesting maternal antibody responses select for these resistant variants during peripartum transmission.

PLoS Pathogens · Apr 19, 2018Peer-reviewedMolecular Biology