David R. Martinez

Endothelial protein C receptor is an entry receptor for Langya and related parahenipaviruses

The paper identifies endothelial protein C receptor (EPCR) as an entry receptor for Langya and related parahenipaviruses and describes the structural basis of this interaction.

Mucosal vaccine-elicited IgA is protective against zoonotic Betacoronavirus challenge

This study shows that intranasal vaccination with a synthetic spike protein and adjuvants elicits durable mucosal IgA and protects against zoonotic SARS-like coronaviruses.

Epitope-Focused Immunogens Confer Broad Protection against Coronaviruses

This study designs epitope-focused immunogens targeting conserved coronavirus regions, showing broad neutralizing activity and protection in mice against diverse coronaviruses.

Broad Sarbecovirus Neutralization by an S2-Directed Plasma Antibody Defines a New Site of Vulnerability in SARS-like Viruses

The paper identifies a broadly neutralizing antibody targeting the S2 subunit of sarbecoviruses, revealing a conserved site of vulnerability in the spike protein.

HKU5 bat merbecoviruses use divergent mechanisms to engage bat and mink ACE2 as entry receptors

This study identifies bat and mink ACE2 as receptors for HKU5 merbecovirus, revealing distinct receptor interactions and highlighting mustelids as potential intermediate hosts.