Author

David S. Moss

Institute of Structural and Molecular Biology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:statistical model· 1

Frequent Co-Authors

Adrian J. ShepherdiD· 1 shared Charlotte B. LewisiD· 1 shared Christopher J. R. IllingworthiD· 1 shared Dalan BaileyiD· 1 shared Giulia GalloiD· 1 shared Irene NobeliiD· 1 shared Joe GroveiD· 1 shared Krzysztof J. SzkopiD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMolecular Biology

Adrian J. ShepherdORCID

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Author profile →

2 papers

Recent·Most cited

An Entropic Safety Catch Controls Hepatitis C Virus Entry and Antibody Resistance.

Lenka Stejskal, Mphatso D. Kalemera, Charlotte B. Lewis, Machaela Palor, Lucas M. Walker, Tina Daviter, William Lees, David S. Moss, Myrto Kremyda-Vlachou, Zisis Kozlakidis, Giulia Gallo, Dalan Bailey, William M. Rosenberg, Christopher J. R. Illingworth, Adrian J. Shepherd, Joe Grove

This study identifies HVR-1 as an autoinhibitory region in HCV E1E2 that suppresses viral entry through conformational entropy, which is released upon receptor binding to enhance entry but reduce antibody resistance.

eLife · Jul 7, 2022Peer-reviewedMolecular Biology

flexiMAP: A regression-based method for discovering differential alternative polyadenylation events in standard RNA-seq data

Krzysztof J. Szkop, David S. Moss, Irene Nobeli

flexiMAP identifies differential alternative polyadenylation in RNA-seq data using beta-regression, outperforming existing methods in sensitivity and specificity.

Bioinformatics · Sep 30, 2020Peer-reviewedBioinformatics