Tryptophan Restores Recovery Competence Following Starvation in the Absence of Lysosomal Amino Acid Sensing
John T. Murphy, Ryan Chang, Ziang Bi, Siana Kapoor, Haoying Zhang, David Seamons, Agastya Diwan, Micklaus Garcia, Moydul Islam, Kenji Rowel Q. Lim, Daniel L. Schneider, Brian M. Egan, David R. Rawnsley, 马秀翠, Kerry Kornfeld, Abhinav Diwan
This study shows that tryptophan restores recovery competence after starvation in C. elegans by countering unrestrained mTOR activity, independent of lysosomal amino acid sensing.
bioRxiv · Oct 28, 2026 · PreprintCell Biology