Telomere-loop dynamics in chromosome end protection
David Van Ly, Ronnie Ren Jie Low, Sonja Frölich, Tara K. Bartolec, Georgia Rose Kafer, Hilda A. Pickett, Katharina Gaus, Anthony J. Cesare
The paper investigates telomere-loop dynamics in chromosome end protection using super-resolution microscopy and finds that t-loops act as conformational switches regulating ATM activation independent of telomere fusion.
Molecular Cell · Jul 20, 2018Peer-reviewedMolecular Biology