Ronnie Ren Jie Low

The paper shows MEN1 deficiency reduces ferroptosis by altering ACSL1 and GPX4 levels, with selenite affecting resistance.

This study identifies distinct roles of ATRX in safeguarding genome and telomere integrity through interactions with CST and 9-1-1 complexes, revealing context-dependent mechanisms.

The paper identifies a CPC-shelterin-BTR axis that regulates mitotic telomere deprotection through phosphorylation events and DDR activation.

This study identifies two parallel pathways regulated by WAPL and telomere deprotection that lead to mitotic death in replication stressed human cells.

The paper investigates telomere-loop dynamics in chromosome end protection using super-resolution microscopy and finds that t-loops act as conformational switches regulating ATM activation independent of telomere fusion.