Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue
Dhruva D. Dhavale, Alexander M. Barclay, Collin G. Borcik, Katherine Basore, Deborah A. Berthold, Isabelle R. Gordon, Jialu Liu, Moses H. Milchberg, Jennifer Y. O’Shea, Michael Rau, Zachary Smith, Soumyo Sen, Brock T. Summers, John W. Smith, Owen A. Warmuth, , Paul T. Kotzbauer
This study determines the atomic structure of alpha-synuclein fibrils from Lewy body dementia tissue using a novel amplification method and solid-state NMR.
Nature Communications · Mar 29, 2024Peer-reviewedNeuroscience