Author

Deborah Y. Kwon

University of Pennsylvania

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Organism:human· 1

Frequent Co-Authors

Hao Wu· 2 shared Zhaolan ZhouiD· 2 shared Bing XuiD· 1 shared Daria ZaitsevaiD· 1 shared Emily B. FabyaniciD· 1 shared Fen‐Biao GaoiD· 1 shared Gopinath KrishnaniD· 1 shared Jennifer E. Phillips‐CreminsiD· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersNeuroscience

Hao Wu

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3 papers

Recent·Most cited

Translation of dipeptide repeat proteins in C9ORF72-ALS/FTD through unique and redundant AUG initiation codons

Yoshifumi Sonobe, Soojin Lee, Gopinath Krishnan, Yuanzheng Gu, Deborah Y. Kwon, Fen‐Biao Gao, Raymond P. Roos, Paschalis Kratsios

The paper identifies AUG initiation codons for antisense DPRs in C9ORF72-ALS/FTD, showing redundancy in start codon usage and distinct translation factors for sense and antisense transcripts.

eLife · Sep 7, 2023Peer-reviewedMolecular Biology

Stress-induced epigenetic regulation of transcription in neocortical excitatory neurons drives depression-like behavior

Deborah Y. Kwon, Bing Xu, Ying-Tao Zhao, Jonathan A. Beagan, Yue Cui, Daria Zaitseva, Jennifer E. Phillips‐Cremins, Julie A. Blendy, Hao Wu, Zhaolan Zhou

The paper identifies epigenetic changes in neocortical excitatory neurons under chronic stress that contribute to depression-like behaviors in mice.

Nature Communications · Jan 10, 2022Peer-reviewedNeuroscience

sNucDrop-Seq: Dissecting cell-type composition and neuronal activity state in mammalian brains by massively parallel single-nucleus RNA-Seq

Peng Hu, Emily B. Fabyanic, Deborah Y. Kwon, Sheng Tang, Zhaolan Zhou, Hao Wu

sNucDrop-Seq isolates nuclei from adult mouse brains to analyze cell-type composition and neuronal activity states at single-nucleus resolution.

Molecular Cell · Dec 1, 2017Peer-reviewedGenomics