Author

Derek C. Lee

Boston College

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

Nathan L. TaiD· 3 shared Purna Mukherjee· 3 shared Thomas N. SeyfriediD· 3 shared Tomás DurajiD· 3 shared Eric Y. MilleriD· 2 shared Michael Kiebish· 2 shared Oscar Shaver· 2 shared Caroline Kornreich· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersCancer Biology

Nathan L. TaORCID

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3 papers

Recent·Most cited

Disentangling the Crabtree and Warburg effects across syngeneic non-tumor and tumor cells.

Tomás Duraj, Eric Y. Miller, Nathan L. Ta, Chloe Lee, Derek C. Lee, Maria Badiola Ramos, Juan J. Aristizabal‐Henao, Michael Kiebish, Purna Mukherjee, Mar Boleda Pellicer, Caroline Kornreich, Oscar Shaver, Thomas N. Seyfried

This study compares bioenergetic profiles of non-tumor and tumor cells to distinguish Crabtree and Warburg effects in mouse cells.

bioRxiv · Oct 7, 2026 · PreprintCancer Biology

The differential effect of glutamine supplementation on the orthotopic and subcutaneous growth of two syngeneic murine models of glioma

J Maurer, Purna Mukherjee, Nathan L. Ta, Derek C. Lee, Tomás Duraj, Juan Henao, Michael Kiebish, Devon Van Cura, Marialucia Herdocia, Thomas N. Seyfried

This study examines the effect of glutamine supplementation on glioma growth in orthotopic and subcutaneous models, finding no effect on orthotopic growth but significant increases in subcutaneous tumor volume.

ONCOLOGIE · Oct 13, 2025Peer-reviewedCancer Biology

Lactate cannot replace glucose for maintaining the viability of mouse and human glioma cells

Eric Y. Miller, Tomás Duraj, Nathan L. Ta, Derek C. Lee, Purna Mukherjee, Oscar Shaver, Thomas N. Seyfried

This study shows lactate cannot replace glucose to maintain viability in mouse and human glioma cells, but supports lactate utilization in non-neoplastic macrophages.

bioRxiv · Jun 3, 2025 · PreprintCancer Biology