Chemical capture of diazo metabolites reveals biosynthetic hydrazone oxidation
Katarina Pfeifer, Devon Van Cura, Kelvin J. Y. Wu, Emily P. Balskus
The paper develops a reactivity-based screening method to capture diazo-containing metabolites, discovering two novel compounds from Nocardia ninae and revealing their biosynthesis via hydrazone oxidation catalyzed by Dob3.