Nathan L. Ta

Disentangling the Crabtree and Warburg effects across syngeneic non-tumor and tumor cells.

This study compares bioenergetic profiles of non-tumor and tumor cells to distinguish Crabtree and Warburg effects in mouse cells.

Intravenous gene therapy improves lifespan and clinical outcomes in feline Sandhoff Disease

Intravenous AAV gene therapy extends lifespan and improves clinical outcomes in feline Sandhoff Disease by reducing GM2 ganglioside accumulation and neuroinflammation.

The differential effect of glutamine supplementation on the orthotopic and subcutaneous growth of two syngeneic murine models of glioma

This study examines the effect of glutamine supplementation on glioma growth in orthotopic and subcutaneous models, finding no effect on orthotopic growth but significant increases in subcutaneous tumor volume.

Lactate cannot replace glucose for maintaining the viability of mouse and human glioma cells

This study shows lactate cannot replace glucose to maintain viability in mouse and human glioma cells, but supports lactate utilization in non-neoplastic macrophages.