Author

Derrick Deming

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Abdolrahim Abbasi· 1 shared Alicia SatoiD· 1 shared Alonso HerediaiD· 1 shared Andrew Asakawa· 1 shared Anthony L. DeVico· 1 shared Arash AslanabadiiD· 1 shared Ben Atkinson· 1 shared Bette KorberiD· 1 shared

Activity by Year

2017-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioengineering

Abdolrahim Abbasi

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Author profile →

2 papers

Recent·Most cited

A Comprehensive Engineering Strategy Improves Potency and Manufacturability of a Near Pan-neutralizing Antibody Against HIV

Mohammad M. Sajadi, Abdolrahim Abbasi, Zahra Rikhtegaran Tehrani, Christine C. Siska, Rutilio H. Clark, Woo Chi, Michael S. Seaman, Dieter Mielke, Kshitij Wagh, Qingbo Liu, Taylor Jumpa, Randal R. Ketchem, Dung Ngoc Pham Nguyen, William David Tolbert, Brian G. Pierce, , Anthony L. DeVico

This study engineers an HIV broadly neutralizing antibody to improve its potency, antiviral activity, and manufacturability while maintaining safety and efficacy.

Structure · May 14, 2025Peer-reviewedBioengineering

The molecular basis for Pompe disease revealed by the structure of human acid α-glucosidase

Derrick Deming, Karen Lee, Tracey McSherry, Ronnie R. Wei, Tim Edmunds, Scott C. Garman

This paper reports the first structure of human acid α-glucosidase, revealing the molecular basis for Pompe disease and pharmacological chaperoning.

bioRxiv · Nov 1, 2017 · PreprintBiochemistry