Author
Evotec (United States)ORCID 0000-0002-7821-2682Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Monika Jain, Sashank Agrawal, Gonzalo Ernesto González-Páez…·Ian A. Wilson
The paper determines the crystal structures of engineered monoclonal antibodies MAM01 and MS-1805 in complex with Plasmodium falciparum CSP, showing retained binding affinity and no significant conformational changes.
Mohammad M. Sajadi, Abdolrahim Abbasi, Zahra Rikhtegaran Tehrani…·Anthony L. DeVico
This study engineers an HIV broadly neutralizing antibody to improve its potency, antiviral activity, and manufacturability while maintaining safety and efficacy.
Rajagopal Murugan, Anton Hanke, Opeyemi Ernest Oludada…·Hedda Wardemann
This study shows that somatic hypermutation increases cross-reactivity of anti-PfCSP antibodies by enhancing flexibility in antigen-bound complexes, but reduces serum stability.