Author

Diana Aguilar

Helmholtz Centre for Infection Research

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Biophysics· 1

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Approach:biophysical modeling· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:structural biology· 1

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Anna K. H. HirschiD· 1 shared Antoine LacouriD· 1 shared Danica J. WalshiD· 1 shared Eleonora DiamantiiD· 1 shared Mostafa M. HamediD· 1 shared Rawia HamidiD· 1 shared

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1 shared paperBiophysics

Anna K. H. HirschORCID

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1 paper

Recent·Most cited

BiophysicsStructurePeer-reviewedNov 6, 2024

IspE Kinase as an Anti-infective Target: Role of a Hydrophobic Pocket in Inhibitor Binding

Rawia Hamid, Danica J. Walsh, Eleonora Diamanti…·Anna K. H. Hirsch

The paper investigates IspE kinase homologs from pathogenic bacteria, identifies structural differences affecting inhibitor binding, and highlights a hydrophobic pocket critical for inhibitor specificity in Acinetobacter baumannii.

3 citations

E. colimouse

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