NeuroscienceCell ReportsPeer-reviewed
DNMT3A haploinsufficiency results in behavioral deficits and global epigenomic dysregulation shared across neurodevelopmental disorders
Diana L. Christian, Dennis Y. Wu, Jenna R. Martin…·Harrison W. Gabel
This study shows that DNMT3A mutations cause behavioral and epigenomic changes in mice, similar to human neurodevelopmental disorders, by disrupting non-CG DNA methylation.
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