Stochastic gene expression is optimized to drive developmental self organization
Ritika Giri, Dimitrios K. Papadopoulos, Diana M. Posadas, Hemanth K. Potluri, Pavel Tomančák, Madhav Mani, Richard W. Carthew
The paper shows that stochastic gene expression, specifically in senseless protein output, is critical for developmental self-organization in Drosophila, with genomic location and microRNA regulation influencing noise and sensory pattern formation.
eLife · Feb 26, 2020Peer-reviewedDevelopmental Biology