Dimitrios K. Papadopoulos

The paper analyzes single-cell Senseless protein dynamics in Drosophila to show metastable states during sensory organ fate transition.

The paper shows that stochastic gene expression, specifically in senseless protein output, is critical for developmental self-organization in Drosophila, with genomic location and microRNA regulation influencing noise and sensory pattern formation.

The paper identifies an ER-localized NMD pathway that regulates the stability of ER-translated mRNAs through the interaction of NBAS and UPF1.

This paper identifies Yorkie's dual role in regulating tracheal tube length and apical barrier integrity in Drosophila airways through cytoplasmic and transcriptional mechanisms.

The paper investigates how variability in Hox transcription factor concentration is controlled during development, finding that an auto-regulatory switch reduces variability by changing the balance of activating and repressing isoforms.