Author

Dimitri Joseph

Michigan State University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Adam A LauveriD· 1 shared Benjamin Scott GlicksbergiD· 1 shared Bin CheniD· 1 shared Dmitry R. LeshchineriD· 1 shared Hannah S. GarveriD· 1 shared Li Huang· 1 shared McKenzie Mahlmeister· 1 shared Nabasmita TalukdariD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperSystems Biology

Adam A LauverORCID

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1 paper

Recent·Most cited

In Vivo Transcriptomics-Based Framework for Systematic Indication Expansion

Zsolt Palmer, Shubham Koirala, Nabasmita Talukdar, Xiaodan Zhang, Hannah S. Garver, McKenzie Mahlmeister, Li Huang, Dimitri Joseph, Dmitry R. Leshchiner, Rama Shankar, Stephanie Wengert Watts, Xiaopeng Li, Benjamin Scott Glicksberg, Adam A Lauver, Bin Chen

This paper presents a drug repurposing framework using in vivo transcriptomics to expand indications by matching drug signatures with disease signatures, successfully recovering established uses of semaglutide and proposing new ones.

bioRxiv · Oct 14, 2026 · PreprintSystems Biology