Human Colon Microphysiological System Reproducing Tissue Mechanical Microenvironment With Active Microfluidic Control and Imaging Capacity
Duvan Rojas-Garcia, Dimitri Hamel, Julie Foncy, Dior Sambe, Sandra Pefaure, Laurent Malaquin, Audrey Ferrand
The paper introduces a human colon microphysiological system that replicates the 3D topography and matrix stiffness of the colon using hydrogels and microfluidic control, enabling long-term culture and imaging of colonic epithelial cells.
bioRxiv · Apr 10, 2025 · PreprintBioengineering