Soma-centered control of synaptic autophagy by Rab39-regulated anterograde trafficking of Atg9
Ayse Kilic, Gökhan Özturan, Dirk Vandekerkhove, Sabine Kuenen, Jef Swerts, Esther Muñoz Pedrazo, Carles Calatayud, Abril Escamilla‐Ayala, Nikky Corthout, Pablo Hernández-Varas, Stéphane Plaisance, Valerie Uytterhoeven, Eliana Nachman, Patrik Verstreken
This study identifies Rab39 as a regulator of autophagy at presynaptic terminals in Drosophila, showing its role in trafficking Atg9 vesicles and its link to neurodegeneration.
The EMBO Journal · Aug 21, 2025Peer-reviewedNeuroscience