Ayse Kilic

PARKINSON'S DISEASE-ASSOCIATED PINK1 LOSS DISRUPTS ENSHEATHING GLIA AND CAUSES DOPAMINERGIC NEURON SYNAPSE LOSS

This study shows that Pink1 loss in Drosophila disrupts ensheathing glia, leading to dopaminergic synapse loss, and identifies vesicle trafficking factors as potential therapeutic targets.

Soma-centered control of synaptic autophagy by Rab39-regulated anterograde trafficking of Atg9

This study identifies Rab39 as a regulator of autophagy at presynaptic terminals in Drosophila, showing its role in trafficking Atg9 vesicles and its link to neurodegeneration.

Behavioral screening defines three molecular Parkinsonism subgroups in Drosophila

The paper identifies three molecular subgroups of parkinsonism in Drosophila using behavioral screening and machine learning, each linked to distinct cellular pathways.