Eliana Nachman

Soma-centered control of synaptic autophagy by Rab39-regulated anterograde trafficking of Atg9

This study identifies Rab39 as a regulator of autophagy at presynaptic terminals in Drosophila, showing its role in trafficking Atg9 vesicles and its link to neurodegeneration.

Neuronal identity defines a-synuclein and tau toxicity

The paper identifies molecular signatures of neuronal vulnerability to α-synuclein and tau toxicity, showing differential susceptibility independent of expression levels.

Disassembly of Tau fibrils by the human Hsp70 disaggregation machinery generates small seeding-competent species

This study shows that the Hsp70 disaggregation machinery disassembles Tau fibrils, generating small seeding-competent Tau species that can drive aggregation.