The neonatal Fc receptor and DPP4 are human astrovirus receptors
Harshad Ingle, Jerome M. Molleston, Paige D. Hall, Duyen Bui, Leran Wang, Karan D. Bhatt, Lynne R. Foster, Avan Antia, Siyuan Ding, Sanghyun Lee, Daved H. Fremont, Megan T. Baldridge
This study identifies FcRn and DPP4 as human astrovirus receptors and shows that targeting these factors with existing inhibitors prevents infection in human enteroid cultures.
Nature Microbiology · Nov 22, 2024Peer-reviewedMicrobiology