Author

E. A. Gould

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Approach:biophysical modeling· 1 Approach:experimental assay· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

X. de Lamballerie· 2 shared A. Nougairede· 1 shared D. Ruzek· 1 shared D. Zouharova· 1 shared E. De Clercq· 1 shared G. Moureau· 1 shared G. Piorkowski· 1 shared J. Haviernik· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMicrobiology

X. de Lamballerie

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2 papers

Recent·Most cited

An E460D substitution in the NS5 protein of tick-borne encephalitis virus confers resistance to the inhibitor Galidesivir (BCX4430) and also attenuates the virus for mice

L. Eyer, A. Nougairede, M. Uhlirova, J.-S. Driouich, D. Zouharova, J. J. Valdes, J. Haviernik, E. A. Gould, E. De Clercq, X. de Lamballerie, D. Ruzek

This paper identifies an E460D substitution in TBEV RdRp that confers resistance to Galidesivir and attenuates the virus in mice.

bioRxiv · Feb 28, 2019Microbiology

Exploratory re-encoding of Yellow Fever Virus genome: new insights for the design of live-attenuated viruses

R. Klitting, T. Riziki, G. Moureau, G. Piorkowski, E. A. Gould, X. de Lamballerie

This study re-encodes the Yellow Fever Virus genome with synonymous mutations to create attenuated strains, finding that certain mutations reduce virulence without significantly affecting replication fitness.

bioRxiv · May 30, 2018Microbiology