Dimerization mechanism of an inverted-topology ion channel in membranes
M. Ernst, E. A. Orabi, R. B. Stockbridge, J. D. Faraldo-Gomez, J. L. Robertson
This study investigates the dimerization mechanism of the inverted-topology fluoride channel Fluc, showing that membrane forces drive assembly while Na+ binding activates the channel.
bioRxiv · Jan 27, 2023Biophysics