Receptor tyrosine kinase inhibition leads to regression of acral melanoma by targeting the tumor microenvironment
E. A. Smith, R. L. Belote, N. M. Cruz, T. E. Moustafa, C. A. Becker, A. Jiang, S. Alizada, T. Y. Chan, T. A. Seasor, M. Balatico, E. Cortes-Sanchez, D. H. Lum, J. R. Hyngstrom, H. Zeng, D. C. Deacon, , R. L. Judson -Torres
This study shows that dual FGFR/VEGFR inhibition causes regression of acral melanoma by targeting the tumor microenvironment rather than directly killing cancer cells.
bioRxiv · Jun 15, 2024Cancer Biology