Intrinsically disordered regions regulate both catalytic and non-catalytic activities of the MutLα mismatch repair complex.
Y. Kim, C. M. Furman, C. M. Manhart, E. Alani, I. J. Finkelstein
The paper shows that intrinsically disordered regions in the yeast MutL complex regulate both DNA binding and enzymatic activities essential for mismatch repair.
bioRxiv · Nov 20, 2018Biochemistry