Supraphysiological protection from replication stress does not extend mammalian lifespan
E. Albers, A. Avram, M. Sbroggio, O. Fernandez-Capetillo, A. J. Lopez-Contreras
This study shows that enhancing replication stress protection in mice does not increase lifespan, suggesting replication stress is not a major driver of normal aging.
bioRxiv · Jan 17, 2020Cancer Biology