ATR expands embryonic stem cell fate potential in response to replication stress
S. Atashpaz, S. Samadi Shams, J. M. Gonzalez, E. Sebestyen, N. Arghavanifard, A. Gnocchi, E. Albers, S. Minardi, G. Faga, P. Soffientini, E. Allievi, V. Cancila, A. Bachi, O. Fernandez-Capetillo, C. Tripodo, , V. Costanzo
This study identifies an ATR-CHK1 pathway in ESCs that enhances fate potential by inducing 2C-like gene expression in response to replication stress.
bioRxiv · Jan 1, 2020Cell Biology