Author

E. Arnaiz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. L. Harris· 2 shared A. Miar· 2 shared J. Rehwinkel· 2 shared A. G. Dias· 1 shared A. P. Cribbs· 1 shared D. J. Downes· 1 shared D. Waithe· 1 shared E. Bridges· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

A. L. Harris

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2 papers

Recent·Most cited

Hypoxia regulates endogenous double-stranded RNA production via reduced mitochondrial DNA transcription

E. Arnaiz, A. Miar, A. G. Dias, N. Prasad, U. Schulze, D. Waithe, J. Rehwinkel, A. L. Harris

The paper shows hypoxia reduces mitochondrial double-stranded RNA production in breast cancer cells, leading to decreased type I IFN signaling and immunosuppression.

bioRxiv · Jul 31, 2020Cancer Biology

Hypoxia induces transcriptional and translational downregulation of the type I interferon (IFN) pathway in multiple cancer cell types

A. Miar, E. Arnaiz, E. Bridges, S. Beedie, A. P. Cribbs, D. J. Downes, R. Beagrie, J. Rehwinkel, A. L. Harris

This study shows hypoxia reduces type I IFN pathway activity in cancer cells through transcriptional and chromatin changes, independent of HIF1/2.

bioRxiv · Jul 25, 2019Cancer Biology