Author

E. Bridges

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 3 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:ATAC-seq· 1

Frequent Co-Authors

A. L. Harris· 3 shared H. Sheldon· 2 shared A. Chatrian· 1 shared A. D. Lamb· 1 shared A. Harris· 1 shared A. L. Magnussen· 1 shared A. Mcintyre· 1 shared A. Miar· 1 shared

Activity by Year

2018-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersCancer Biology

A. L. Harris

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4 papers

Recent·Most cited

Tumor irradiation combined with vascular-targeted photodynamic therapy enhances anti-tumor effects in preclinical prostate cancer.

H. T. Sjoberg, Y. J. Philippou, A. L. Magnussen, I. D. Tullis, E. Bridges, A. Chatrian, J. Loefebvre, K. H. Tam, E. A. Murphy, J. Rittscher, D. Preise, L. Agemy, T. Yechezkel, S. C. Smart, P. Kinchesh, , R. J. Bryant

This paper investigates combining fractionated radiotherapy with vascular-targeted photodynamic therapy to enhance tumor control in preclinical prostate cancer models.

bioRxiv · Nov 26, 2020 · PreprintCancer Biology

Glutamine deprivation regulates the origin and function of cancer cell exosomes

D. Goberdhan, S.-J. Fan, B. Kroeger, P. Marie, E. Bridges, J. Mason, K. McCormick, C. Zois, H. Sheldon, N. Khalid Alham, E. Johnson, M. Elis, I. Stefana, C. Mendes, M. Wainwright, , C. Wilson

This study shows that glutamine deprivation increases exosome release from cancer cells, which promote tumor growth and blood vessel networks through Rab11a-dependent mechanisms.

bioRxiv · Dec 2, 2019Cancer Biology

Hypoxia induces transcriptional and translational downregulation of the type I interferon (IFN) pathway in multiple cancer cell types

A. Miar, E. Arnaiz, E. Bridges, S. Beedie, A. P. Cribbs, D. J. Downes, R. Beagrie, J. Rehwinkel, A. L. Harris

This study shows hypoxia reduces type I IFN pathway activity in cancer cells through transcriptional and chromatin changes, independent of HIF1/2.

bioRxiv · Jul 25, 2019Cancer Biology

Hypoxia-induced switch in SNAT2/SLC38A2 regulation generates endocrine-resistance in breast cancer

M. Morotti, E. Bridges, A. Valli, H. Choudhry, H. Sheldon, S. Wigfield, N. Gray, D. Jones, E. J. Teoh, W.-C. Cheng, S. Lord, S. Haider, A. Mcintyre, D. C. I. Goberdhan, F. Buffa, A. L. Harris

This study shows hypoxia shifts SNAT2 regulation from ER to HIF-1 in breast cancer, leading to endocrine resistance and poor outcomes.

bioRxiv · Aug 3, 2018Cancer Biology