Stimulator of interferon genes is required for Toll-Like Receptor-8 induced interferon response
K. Y. Garcia-Martinez, J. Chen, J. Jones, A. Woo, E. Aucapina, I. L. Brito, C. A. Leifer
This study shows that STING is required for TLR8-induced IFN production in human monocytes and reveals a new crosstalk mechanism between cytosolic and endosomal innate immune receptors.
bioRxiv · May 15, 2023 · PreprintImmunology