C. A. Leifer

Stimulator of interferon genes is required for Toll-Like Receptor-8 induced interferon response

This study shows that STING is required for TLR8-induced IFN production in human monocytes and reveals a new crosstalk mechanism between cytosolic and endosomal innate immune receptors.

Gut microbiota influence B cell function in a TLR5-dependent manner

This study shows TLR5 signaling in epithelial cells affects B cell populations and antibody responses, leading to microbiome dysbiosis in TLR5-deficient mice.