Author

E. Bruguera

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

H. Matsunami· 2 shared C. A. de March· 1 shared I. Spasojevic· 1 shared J. R. Bain· 1 shared K. Ikegami· 1 shared M. Do· 1 shared M. J. Muehlbauer· 1 shared M. Nagai· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

H. Matsunami

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2 papers

Recent·Most cited

Structural instability and divergence from conserved residues underlie intracellular retention of mammalian odorant receptors

K. Ikegami, C. A. de March, M. Nagai, S. Ghosh, M. Do, R. Sharma, E. Bruguera, Y. Lu, Y. Fukutani, N. Vaidehi, M. Yohda, H. Matsunami

This study identifies structural instability and divergence from conserved residues as causes of intracellular retention of odorant receptors, using computational and experimental methods.

bioRxiv · Dec 4, 2019Cell Biology

A testosterone metabolite 19-hydroxyandrostenedione induces neuroendocrine trans-differentiation of prostate cancer cells via an ectopic olfactory receptor

T. Abaffy, J. R. Bain, M. J. Muehlbauer, I. Spasojevic, S. Lodha, E. Bruguera, S. K. Neal, S. Y. Kim, H. Matsunami

This study identifies 19-hydroxyandrostenedione as an endogenous agonist of OR51E2 that induces neuroendocrine trans-differentiation in prostate cancer cells.

bioRxiv · Jan 4, 2018Cancer Biology