Transcriptome analysis of FOXO-dependent hypoxia gene expression identifies Hipk as a regulator of low oxygen tolerance in Drosophila
K. Ding, E. C. Barretto, M. Johnston, B. Lee, M. Gallo, S. S. Grewal
The paper identifies FOXO-dependent gene expression changes in Drosophila under hypoxia, revealing Hipk as a key regulator of hypoxia survival and uncovering FOXO's role in suppressing energy-intensive processes.
bioRxiv · Jun 17, 2022Physiology