Author

S. S. Grewal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 4 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:metabolism & bioenergetics· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

B. Lee· 4 shared E. C. Barretto· 2 shared A. N. Beevor-Potts· 1 shared D. M. Polan· 1 shared K. Ding· 1 shared M. Gallo· 1 shared M. Johnston· 1 shared R. Deshpande· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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4 shared papersPhysiology

B. Lee

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4 papers

Recent·Most cited

Transcriptome analysis of FOXO-dependent hypoxia gene expression identifies Hipk as a regulator of low oxygen tolerance in Drosophila

K. Ding, E. C. Barretto, M. Johnston, B. Lee, M. Gallo, S. S. Grewal

The paper identifies FOXO-dependent gene expression changes in Drosophila under hypoxia, revealing Hipk as a key regulator of hypoxia survival and uncovering FOXO's role in suppressing energy-intensive processes.

bioRxiv · Jun 17, 2022Physiology

Enteric bacterial infection in Drosophila induces whole-body alterations in metabolic gene expression independently of the Immune Deficiency (Imd) signalling pathway.

R. Deshpande, B. Lee, S. S. Grewal

This study shows that Drosophila infected with Pseudomonas entomophila exhibit increased metabolic gene expression and altered transcription factors, independent of the Imd pathway.

bioRxiv · May 11, 2022 · PreprintPhysiology

TOR signalling is required for host lipid metabolic remodelling and survival following enteric infection in Drosophila

R. S. Deshpande, B. Lee, Y. Qiao, S. S. Grewal

This study identifies TOR signalling as critical for lipid metabolic remodelling and survival in Drosophila during enteric infection.

bioRxiv · Jul 12, 2021Physiology

FOXO mediates organismal hypoxia tolerance by regulating NF-κB in Drosophila

E. C. Barretto, D. M. Polan, A. N. Beevor-Potts, B. Lee, S. S. Grewal

This study shows FOXO mediates hypoxia tolerance in Drosophila by inducing NF-κB/Relish expression, which regulates glucose metabolism and survival under low oxygen.

bioRxiv · Jun 22, 2019 · PreprintCell Biology