Phosphatidylinositol 3,5-Bisphosphate regulates Ca2+ Transport During Yeast Vacuolar Fusion through Activation of the Ca2+ ATPase Pmc1
G. E. Miner, K. D. Sullivan, A. Guo, M. L. Starr, E. C. Ellis, B. C. Jones, R. A. Fratti
This study shows that PI(3,5)P2 regulates Ca2+ transport in yeast vacuoles by activating Pmc1 during fusion, opposing its role in fission.
bioRxiv · Feb 1, 2019Biochemistry