Reactive myelopoiesis and FX-expressing monocyte-derived macrophages triggered by chemotherapy promote cancer lung metastasis
C. Wu, Q. Zhong, R. Shrestha, J. Wang, X. Hu, H. Li, E. C. Rouchka, J. Yan, C. DING
This study shows chemotherapy-induced reactive myelopoiesis and FX-expressing macrophages promote cancer lung metastasis through CCL2/CCR2 axis and coagulation-inflammation interplay.
bioRxiv · Dec 7, 2022 · PreprintImmunology