Circumventing drug treatment? Polyethylenimine functionalized nanoparticles inherently and selectively kill patient-derived glioblastoma stem cells
N. Prabhakar, J. Merisaari, V. Le Joncour, M. Peurla, D. Sen Karaman, E. Casals, P. Laakkonen, J. Westermarck, J. Rosenholm
This study shows that PEI-functionalized nanoparticles selectively kill glioblastoma stem cells by lysosomal membrane rupture without affecting other cancer cells.
bioRxiv · Dec 14, 2020 · PreprintCancer Biology