Author

E. Charles

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Organism:E. coli· 1

Frequent Co-Authors

A. Salvetti· 2 shared D. Durantel· 2 shared F. Pastor· 2 shared G. Passot· 2 shared J. Lucifora· 2 shared M. Rivoire· 2 shared A. Aindow· 1 shared A. Deep· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMicrobiology

A. Salvetti

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

THE DUAL-SPECIFICITY KINASE DYRK1A INTERACTS WITH THE HEPATITIS B VIRUS GENOME AND REGULATES THE PRODUCTION OF VIRAL RNA

F. Pastor, E. Charles, C. Di Vona, M. Chapelle, M. Rivoire, G. Passot, B. Chabot, S. de la Luna, J. Lucifora, D. Durantel, A. Salvetti

This study identifies DYRK1A as a kinase that interacts with HBV cccDNA and enhances HBV RNA production by regulating the enhancer 1/X promoter.

bioRxiv · May 30, 2024Microbiology

Deciphering the phospho-signature induced by hepatitis B virus in primary human hepatocytes

F. Pastor, E. Charles, L. Belmudes, H. Chabrolles, M. Cescato, M. Rivoire, T. Burger, G. Passot, D. Durantel, J. Lucifora, Y. Coute, A. SALVETTI

This study identifies phosphorylation changes in host proteins induced by HBV infection in primary human hepatocytes, revealing an intrinsic anti-viral response involving DNA repair and RNA-binding proteins.

bioRxiv · Apr 10, 2024Microbiology

A transcriptionally active lipid vesicle encloses theinjected Chimalliviridae genome in early infection

E. Armbruster, P. Rani, J. Lee, N. Klusch, J. Hutchings, L. Y. Hoffman, H. Buschkaemper, E. Enustun, B. Adler, K. Inlow, A. VanderWal, M. Y. Hoffman, D. Daksh, A. Aindow, A. Deep, , J. Pogliano

The paper shows that Chimalliviridae form a lipid membrane-bound EPI vesicle during early infection, which hosts transcription of the phage genome, and demonstrates the necessity of a second compartment, the phage nucleus, for genome replication.

bioRxiv · Sep 20, 2023 · PreprintCell Biology

Inhibition of MreB and ftsZ proteins to minimize E. coli biofilm formation

This study investigates the effects of MreB and ftsZ inhibitors on E. coli biofilm formation, finding that A22 reduces biofilm density and is as effective as Amoxicillin.

bioRxiv · Jan 17, 2019 · PreprintMicrobiology