Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
9 papers
Recent·Most cited
F. Pastor, E. Charles, L. Belmudes, H. Chabrolles, M. Cescato, M. Rivoire, T. Burger, G. Passot, D. Durantel, J. Lucifora, Y. Coute, A. SALVETTI
This study identifies phosphorylation changes in host proteins induced by HBV infection in primary human hepatocytes, revealing an intrinsic anti-viral response involving DNA repair and RNA-binding proteins.
bioRxiv · Apr 10, 2024Microbiology
A. G. Casanova, G. S. Roth, S. Hausmann, X. Lu, L. Belmudes, E. Bourova-Flin, N. M. Flores, A. M. Benitez, M. Caporicci, J. Vayr, S. Blanchet, F. Ielasi, S. Rousseaux, P. Hainaut, O. Gozani, , N. Reynoird
This study identifies SMYD2 as a master regulator of breast cancer metastasis and shows that targeting the SMYD2-BCAR3-FMNL axis can prevent metastatic spread.
bioRxiv · Sep 18, 2023Cancer Biology
J.-M. Alempic, H. Bisio, A. Villalta, S. Santini, A. Lartigue, A. Schmitt, C. Bugnot, A. Notaro, L. BELMUDES, A. Adrait, O. Poirot, D. Ptchelkine, C. De Castro, Y. Coute, C. Abergel
The study shows that deleting GMC-oxidoreductase genes in mimiviruses does not impair genomic fiber or fibril layer formation, indicating functional redundancy.
bioRxiv · Apr 28, 2023Microbiology
A. Kairouani, D. Pontier, C. Picart, F. Mounet, Y. Martinez, L. Le-Bot, M. Fanuel, P. Hammann, L. Belmudes, R. Merret, J. Azevedo, M.-C. Carpentier, D. Gagliardi, Y. Coute, R. Sibout, , T. LAGRANGE
This study identifies MSIL2 and MSIL4 as cell type-specific regulators of secondary cell wall formation in Arabidopsis by controlling mRNA translation and biosynthetic gene expression.
bioRxiv · Mar 20, 2023 · PreprintPlant Biology
A. Villalta, A. Schmitt, L. F. Estrozi, E. R. J. Quemin, A. Lartigue, J.-M. Alempic, V. Prazak, L. Belmudes, D. Vasishtan, A. M. G. Colmant, F. A. Honore, Y. Coute, K. Grünewald, C. Abergel
The paper reveals the Mimivirus genome is organized into a 30 nm helical protein shell with super-helical DNA strands and a central channel accommodating transcription machinery.
bioRxiv · Feb 17, 2022Microbiology
C. SWALE, V. BELLINI, M. W. Bowler, F. NARDELLA, M.-P. Brenier-Pinchart, D. Cannella, L. Belmudes, C. MAS, Y. Coute, F. LAURENT, A. Scherf, A. BOUGDOUR, M.-a. HAKIMI
This paper identifies altiratinib as a selective inhibitor of PRP4K/CLK3 kinases in apicomplexan parasites, showing broad-spectrum antiparasitic activity against toxoplasmosis and malaria.
bioRxiv · Nov 3, 2021 · PreprintMicrobiology
D. C. Farhat, M. W. Bowler, G. Communie, D. PONTIER, L. Belmudes, C. MAS, C. Corrao, Y. COUTE, A. BOUGDOUR, T. LAGRANGE, M.-a. HAKIMI, C. Swale
This paper identifies an m6A-dependent polyadenylation mechanism in Toxoplasma gondii that prevents transcriptional read-through and maintains transcriptome integrity, similar to a plant mechanism.
bioRxiv · Feb 23, 2021Microbiology
H. Chabrolles, H. Auclair, S. Vegna, T. Lahlali, C. Pons, M. Michelet, Y. Coute, L. Belmudes, Y. Kim, A. Di Bernardo, P. Jalaguier, M. Rivoire, L. D. Arnold, U. Lopatin, C. Combet, , A. SALVETTI
This study identifies SRSF10 as a host RNA-binding protein that restricts HBV RNA production by interacting with the HBV core protein in the nucleus of infected hepatocytes.
PLOS Pathogens · Nov 12, 2020Peer-reviewedMicrobiology
S. Jeudy, L. Bertaux, J.-M. Alempic, A. Lartigue, M. Legendre, L. Belmudes, S. Santini, N. Philippe, L. Beucher, E. G. Biondi, S. Juul, D. J. Turner, Y. Coute, J.-M. Claverie, C. Abergel
This study investigates the interaction network between a virophage, transpovirons, and their host giant viruses, revealing a form of commensalism where transpovirons use virophages to propagate without affecting the host virus's infectious cycle.
bioRxiv · Sep 25, 2019 · PreprintMicrobiology